Evaluation of a novel Scheimpflug-based non-contact tonometer in healthy subjects and patients with ocular hypertension and glaucoma

Background: To evaluate the agreement of intraocular pressure (IOP)
and central corneal thickness (CCT) measurements obtained with the
non-contact tonometer Corvis Scheimpflug Technology (Corvis ST,
OCULUS, Wetzlar, Germany) versus Goldmann applanation tonometry
(GAT) and ultrasound-based corneal pachymetry (US-CCT). Methods:
Eye healthy participants, patients with ocular hypertension (OHT)
and patients with open-angle glaucoma were included in this
prospective study. In each participant, GAT, US-CCT and
measurements with Corvis ST were obtained (Corvis-IOP and
Corvis-CCT). Accuracy and repeatability were tested by correlation
and regression analyses, Bland-Altman plots and assessment of
intraclass correlation coefficients. Results: A consecutive series
of 188 right study eyes of 188 participants (142 eyes with
glaucoma, 10 eyes with OHT and 36 control eyes) were included in
this prospective study. The mean GAT of all included was
14.54.8mmHg compared with mean Corvis-IOP of 15.4 +/- 5.6mmHg
(Spearman's r=0.75, p