Water immersion increases the concentration of the immunoreactive N-terminal fragment of pro-atrial natriuretic factor in human plasma

Atrial natriuretic factor (ANF) N-terminal (ANF 1–98) and
C-terminal (ANF 99–126) fragments were determined by
radioimmunoassay in human plasma. Mean basal plasma ANF N-terminal
concentrations in 9 healthy subjects were 461 ± 58
fmol/ml,significantly (p